running with blisters

I agree with the post above on how to treat the blister.  For me, it's usually the socks that cause blisters.  They have a tendancy to slide in the shoe and your foot.  I use my cycling socks (tight socks made from a technical material) for anything more than an hour of running.  I've had good luck with using body glide, especially on the toes and then Defeet socks.  I usually just buy the overprint ones from Performance.   Good luck.

Ernie 

If you drain the blister it won't be as painful- I promise That's my recommendation.  I use a sterilize needle (make sure it's sterile) and drain the blister.  Don't put anything like Neosporin on them or something that's going to keep the skin moist- you want it to dry up.  Try soaking your feet in epsom salt/water/vinegar.  The salt will help dry up the sky and the vinegar will kill any germs in the water to prevent infection.  To dry up the skin I use betadine- you can buy it at Wal-Mart and it'll dry the skin and toughen it up really fast!  It works wonders on blisters!

BTW- I was able to run with these blisters after doing the above, so your blister should be fine once you drain it!

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When backpacking and climbing deep  in the backcountry you don't have a choice but to take care of your blisters.  You can't call for rescue because you have booboo on your toe.

Use a needle and drain the fluid from the blister, be very careful not to remove the upper layer of skin as that will serve as your band-aid and will help the blister heal faster.

Get some Moleskin and cut a square out of it.

Place it over your blister, noting the size of the blister.

Cut a circular hole in the moleskin so that the moleskin will not stick to the blister (this can be very bad if it sticks to the blister, when you remove the moleskin you will pull off the flap of skin).

Apply that piece of moleskin over the blister and place a square cut piece of moleskin over the top of that.

Essentially what you have just created greatly resembles a corn pad with out the medication inside.

 Moleskin will stick to your skin and will not move around like a typical band-aid will.  It will stay on until you are ready to remove it or it will come off on it's own in a few days.  In most cases your blister is already healed by the time the Moleskin comes off.  Moleskin, Moleskin +, and MoleFoam are available in roles and are very inexpensive.  This may sound like a complicated process, but in all actuality it is very easy, very quick and works wonderfully.  I walked down 7000 feet last year when I climbed Mt. Blanca with moleskin on my feet and didn't have any pain.  I have also used this method in very wet conditions while backpacking in East Texas.