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2011-08-02 12:28 PM

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Subject: Tour de France rider suffers blood clot, be aware

Chris Horner got a pulmonary embolism following his Tour de France crash

http://www.cascadegranfondo.com/blog/what-i-did-my-summer-vacation%E2%80%A6

You might think this is a Peloton forum or Health or Cup of Joe forum topic, but anyone doing longer endurance events needs to be aware of the risks.  It's not just out of shape people, or people on long flights, or women on birth control.  In fact one study concluded that the majority of people getting blood clots were marathoners.

Dehydration, micro damage to muscles, low heart rate, immobilization from injury, or a long car ride home, are all risk factors.  Know the risk factors and avoid them if at all possible and manage them otherwise



Edited by ChrisM 2011-08-02 12:31 PM


2011-08-02 12:44 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware
Thanks for posting this.  I have seen many posts from you on this topic, and it has helped keep the issue in my mind so I'm more aware of the risk factors and symptoms.  On the long drive home from my 1/2 IM this past weekend I made sure to stay hydrated and keep my legs moving as much as possible!
2011-08-02 12:51 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware

Dehydration, micro damage to muscles, low heart rate, immobilization from injury, or a long car ride home, are all risk factors.  Know the risk factors and avoid them if at all possible and manage them otherwise

Risk factors like blood doping?

I'm not at all surprised to see this happen to a Tour rider.

2011-08-02 12:52 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware
spudone - 2011-08-02 1:51 PM

Dehydration, micro damage to muscles, low heart rate, immobilization from injury, or a long car ride home, are all risk factors.  Know the risk factors and avoid them if at all possible and manage them otherwise

Risk factors like blood doping?

I'm not at all surprised to see this happen to a Tour rider.

yes... or flying... or quite a few other things.

2011-08-02 1:03 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware
Leegoocrap - 2011-08-02 10:52 AM
spudone - 2011-08-02 1:51 PM

Dehydration, micro damage to muscles, low heart rate, immobilization from injury, or a long car ride home, are all risk factors.  Know the risk factors and avoid them if at all possible and manage them otherwise

Risk factors like blood doping?

I'm not at all surprised to see this happen to a Tour rider.

yes... or flying... or quite a few other things.

That's true and in this case it was most likely caused by the hematoma received in his crash.  Similar thing happened to Serena Williams:

http://www.cbsnews.com/stories/2011/03/02/sports/main20038228.shtml

2011-08-02 1:08 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware
spudone - 2011-08-02 1:03 PM
Leegoocrap - 2011-08-02 10:52 AM
spudone - 2011-08-02 1:51 PM

Dehydration, micro damage to muscles, low heart rate, immobilization from injury, or a long car ride home, are all risk factors.  Know the risk factors and avoid them if at all possible and manage them otherwise

Risk factors like blood doping?

I'm not at all surprised to see this happen to a Tour rider.

yes... or flying... or quite a few other things.

That's true and in this case it was most likely caused by the hematoma received in his crash.  Similar thing happened to Serena Williams:

http://www.cbsnews.com/stories/2011/03/02/sports/main20038228.shtml


so.....ummmm.....we should forget that you were basically implying that Chris Horner is a doper???????????


2011-08-02 1:15 PM
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Subject: ...
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2011-08-02 1:20 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware
Birkierunner - 2011-08-02 11:08 AM
spudone - 2011-08-02 1:03 PM
Leegoocrap - 2011-08-02 10:52 AM
spudone - 2011-08-02 1:51 PM

Dehydration, micro damage to muscles, low heart rate, immobilization from injury, or a long car ride home, are all risk factors.  Know the risk factors and avoid them if at all possible and manage them otherwise

Risk factors like blood doping?

I'm not at all surprised to see this happen to a Tour rider.

yes... or flying... or quite a few other things.

That's true and in this case it was most likely caused by the hematoma received in his crash.  Similar thing happened to Serena Williams:

http://www.cbsnews.com/stories/2011/03/02/sports/main20038228.shtml


so.....ummmm.....we should forget that you were basically implying that Chris Horner is a doper???????????

I implied that Tour riders, are generally not clean and no, you don't have to forget I said it.

2011-08-02 1:42 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware

Wow, Tour riders in general? Why not all pro riders? Why not ALL riders?  Why not triathletes? 

Apologies to the OP for polluting your helpful PSA.  Given the severity of the Horner crash, he's lucky it wasn't a cerebral embolism.  If you saw the freaky footage of him being carted off, asking repeatedly if he'd finished, you'd think he's lucky to be alive.

2011-08-02 2:00 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware

tkos - 2011-08-02 2:15 PM And just to be aware that while things liek EPO certainly can't help in these cases, the UCI put out a list of suspected riders scored from 0 - 10 (well leaked out), and Horner was listed as a zero with a handful of other guys.

I will say... that list looked like a joke, and I like almost every guy that scored a 0.

2011-08-02 2:05 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware
spudone - 2011-08-02 2:20 PM
Birkierunner - 2011-08-02 11:08 AM
spudone - 2011-08-02 1:03 PM
Leegoocrap - 2011-08-02 10:52 AM
spudone - 2011-08-02 1:51 PM

Dehydration, micro damage to muscles, low heart rate, immobilization from injury, or a long car ride home, are all risk factors.  Know the risk factors and avoid them if at all possible and manage them otherwise

Risk factors like blood doping?

I'm not at all surprised to see this happen to a Tour rider.

yes... or flying... or quite a few other things.

That's true and in this case it was most likely caused by the hematoma received in his crash.  Similar thing happened to Serena Williams:

http://www.cbsnews.com/stories/2011/03/02/sports/main20038228.shtml


so.....ummmm.....we should forget that you were basically implying that Chris Horner is a doper???????????

I implied that Tour riders, are generally not clean and no, you don't have to forget I said it.

 

I always love the generic doping accusations with nothing to back it up



2011-08-02 2:05 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware
spudone - 2011-08-02 3:20 PM

I implied that Tour riders, are generally not clean and no, you don't have to forget I said it.



How would you analyze the cleanliness of riders at this year's events?

Shane
2011-08-02 3:40 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware
So, sorry if this is a simple question, but what can one do to minimize the risk?  Stay hydrated.  Don't sit too long.  Anything else?
2011-08-02 5:08 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware

 

I always love the generic doping accusations with nothing to back it up



*Facepalm*
2011-08-02 5:09 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware

ersmith29 - 2011-08-02 1:40 PM So, sorry if this is a simple question, but what can one do to minimize the risk?  Stay hydrated.  Don't sit too long.  Anything else?

Thanks for bringing it back on topic.  Doping debaters, please go somewhere else.

Anyway, those are the two main ones, but there are others, including potentially the use of compression gear (which is debatable on recent studies), related to dehydration but avoid alcohol around racing, don't stop moving right after a race, walk around a bit and keep the blood flowing.  From the National Blood Clot Alliance article re: athletes:

 

  • Take breaks and stretch legs when traveling long distances;

  • Stay well hydrated (during and after a strenuous sporting event and travel);

  • Know the symptoms of DVT and PE and seek early medical attention if they occur;

  • Realize that DVT and PE can occur in the athlete;

  • Know the risk factors for blood clots (see table 1);

  • Know whether you have a family history of blood clots;

  • In case of major surgery, trauma, prolonged immobility, or when in a cast: ask your doctor whether you should receive DVT prophylaxis and, if yes, for how long.

2011-08-02 5:36 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware

Anyway, those are the two main ones, but there are others, including potentially the use of compression gear (which is debatable on recent studies

Curious as to why compression gear is debatable.  Don't they use compression socks, etc in hospitals for this reason? 



2011-08-02 5:40 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware
buck1400 - 2011-08-02 3:36 PM

Anyway, those are the two main ones, but there are others, including potentially the use of compression gear (which is debatable on recent studies

Curious as to why compression gear is debatable.  Don't they use compression socks, etc in hospitals for this reason? 

They do, but there was a recent hospital (can't recall the name) that stopped recommending them claiming they did not actually do anything to prevent DVTs

2011-08-02 5:42 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware
ctbrian - 2011-08-02 2:05 PM

I always love the generic doping accusations with nothing to back it up

 

Here's 2010

2010

 

  • On 29 January 2010, Italian Vania Rossi was reported positive for CERA by the Italian Olympic Committee. The Comitato Olimpico Nazionale Italiano (CONI) controlled Rossi on January 10 after she finished second in the women's national cyclocross championships. Her B sample subsequently came back negative. Rossi is the partner of Italian professional cyclist Riccardo Riccò, who himself tested positive for CERA at the 2008 Tour de France.[374] Her B sample later came back negative, and she was cleared of all charges.[375]
  • On 11 March, Polish brothers Pawel and Kacper Szczepaniak, who finished first and second in the under 23 race of the 2010 UCI Cyclo-cross World Championships, have returned positive results for EPO, in controls carried out at the event which took place in Tabor, Czech Republic in January. The two had been targeted after suspicious blood profiles were revealed as part of their respective biological passports. Their B samples will have to be analysed before any suspension is handed out.[376] A week later, Kacper Szczepaniak reportedly attempted to commit suicide.[377]
  • Manuel Vazquez Hueso of Spain was found, on 14 March, to have taken EPO, and in January 2011 the UCI handed down a fine of €35,000 and suspension until April 2012.[378]
  • On 16 March 2010, Alejandro Valverde's appeal against his ban from riding in Italy was rejected by the Court of Arbitration for Sport. It was confirmed that he could not ride on Italian soil again until 10 March 2011. A UCI press statement, issued after this hearing, stated that "the UCI expresses its determination to take the necessary measures to secure a suspension that is applicable internationally."[379] The UCI President Pat McQuaid stated later that it will seek to extend Valverde's ban worldwide.[380] On 27 March, McQuaid said that the UCI will wait to impose a worldwide ban on Valverde until CAS rules on an appeal by the UCI, protesting the fact that the Spanish cycling federation (RFEC) did not open disciplinary proceedings against Valverde. The CAS ruled on 31 May that the suspension could be enforced, and the UCI applied a retroactive two year suspension on Valverde from 1 January 2010. In additionto this, all of his results from 2010 were nullified.[381]
  • On 6 April 2010, Italian newspaper La Gazzetta dello Sport revealed that a doping investigation based around the town of Mariana Mantovana in Lombardy had been commenced by Italian police. It reported that the investigation could involve 54 people relating to events in the 2008 and 2009 seasons. The cycling coach/doctor Guido Negrelli, who has worked in the past with Lampre riders and the team manager Giuseppe Saronni is allegedly at the centre of the investigation. Lampre-Farnese Vini's team doctors and two riders, Alessandro Petacchi and Lorenzo Bernucci, had their homes searched as part of the investigation. Bernucci was suspended after police reportedly found banned products in his house. He remains suspended until his team receive further information about the search.[382] A day later, the same newspaper revealed more details of the investigation, claiming that 16 of the teams riders and staff had been placed under formal investigation for doping related offences. Amongst the names mentioned by the newspaper are current and former Lampre riders, including Francesco GavazziDamiano CunegoAlessandro Ballan, and Mauro Santambrogio (Both now at BMC Racing Team). Team manager Saronni, directeur sportifs Fabrizio Bontempi and Maurizio Piovani, current coach Sergio Gelati, and former Lampre doctor Dr Andrea Andreazzoli (now at Astana Team were also named.[383] On 9 April, BMC Racing suspended its riders Ballan and Santambrogio pending the outcome of the police investigation.[384]
  • Also on 22 April 2010, the UCI announced that Team Radio Shack rider Li Fuyu had tested positive for the banned substance clenbuterol during the Dwars door Vlaanderen on March 23. He has been suspended by his team pending the outcome of the B sample testing.[386]
  • On 28 April, it was announced that Gabriele Bosisio would be suspended from professional cycling for 2 years. He tested positive for EPO in an out-of-competition test in September 2009. He was provisionally suspended by the UCI on October 6, and so his ban will end on 5 October 2011.[387]
  • On 3 May, the UCI announced the names of three riders who had returned irregular blood values in their blood passport. These riders were Franco PellizottiJesus Rosendo Prado and Tadej Valjavec.[388] On 22 June, the Spanish Cycling Federation cleared Rosendo.[389] On 30 July, Valjavec was cleared by the Slovenian anti-doping agency.[390] On 21 October, Pellizotti was also cleared by his own national anti-doping agency.[391] The UCI is expected to appeal these decisions.
  • One day later, on 4 May, it was announced that French rider Mickaël Larpe had tested positive for EPO, ten hours after his house was raided by police.[392]
  • On 27 May, Francesco De Bonis became the first cyclist to be banned on the evidence of his blood passport results. His 2 year suspension will finish in June 2011, 2 years after he was first stopped from racing.[393]
  • On 3 June, it was announced that Pietro Caucchioli had been banned for 2 years on the evidence of his irregular blood passport results, found in June 2009. His ban will finish in June 2011.[394]
  • On 17 June, the UCI announced that Ricardo Serrano had been suspended by the Spanish cycling federation (RFEC) for two years due to CERA having been found in two separate blood samples collected around a year ago. He was also implicated due to abnormal values in his blood passport.[395]
  • On 20 June, media reports told of how Alessandro Petacchi had been notified at the start of the Tour de France that he had been placed under investigation by a prosecutor in Padova. Petacchi is accused of having used PFC (Perfluorocarbon) and human serum albumin.[396] The accusations stem from phone taps on a doctor from Brescia.[397]
  • On 7 July, it was announced that Niklas Axelsson had been suspended for life following positive analysis of his B-sample for EPO. He had previously been suspended for EPO use in 2001.[398]
  • Three Brazilian riders were sanctioned for adverse findings during the Tour do Rio in July 2010: Jao Paulo de Oliveira (for phentermine) and two for stanazolol: Lucas Onesco and Jair Fernando dos Santos. All three received a two year suspension and loss of results.[399]
  • On 29 July, the UK Anti-doping agency posted the 2 year suspension for cyclist Dan Staite for EPO and ATD found in sample taken at a National B level event.[400]
  • On 8 September, while he was riding the 2010 Vuelta a España, it was announced that Roy Sentjens had failed an out of competition doping control and would be suspended from cycling.[401] On September 10, Sentjens admitted to having doped with EPO that he had obtained in Barcelona, Spain, and declined to request the testing of his B-sample. He also announced his immediate retirement from professional cycling.[402]
  • On 16 September, a UCI statement was released announcing that Óscar Sevilla had tested positive for the blood expander Hydroxyethyl starch after the final stage of the Vuelta a Colombia, which he had won, on 15 August.He has been provisionally suspended.[403] On 30 September, it was announced that the Spanish Cycling Federation will let him continue racing until his B-sample is tested.[404]
  • On 29 September, a UCI statement was released announcing that this year's Tour de France winner, Alberto Contador, had tested positive for "a very small concentration" of the banned stimulant clenbuterol, on July 21, one of the race's rest days. He has been provisionally suspended by the UCI.[405]
  • On 30 September, the UCI announced that Xacobeo-Galicia riders Ezequiel Mosquera and David García Dapena had both tested positive for Hydroxyethyl starch on September 16, during the Vuelta a Espana. Mosquera had finished the race in 2nd place, and Dapena finished 11th overall.[406] On 6 October, it was announced that Garcia Dapena had tested positive for EPO during the race, on 13 September.[407]
  • On 7 October, Joao Benta admitted to doping after having tested positive in July.[408]
  • On 9 October, Alessandro Colo was given a one-year ban by CONI for testing positive for clenbuterol on the last stage of the Vuelta Mexico.[409]
  • On 18 October, two Portuguese riders - Rui Costa and his brother Mario - were announced as having tested positive for the substance Methylhexanamine. The samples were taken during the Portuguese National Championships at the end of June.[410]Their ban was reduced to 5 months, rather than the standard 2 years, as they were able to satisfy the panel that this was a case of accidental ingestion, via a contaminated supplement.[411]

 

 

http://en.wikipedia.org/wiki/List_of_doping_cases_in_cycling

 

Here's the rest complete with 419 annotations. That took 30 seconds, any more "proof" you'd like?

 

2011-08-02 9:21 PM
in reply to: #3625595

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Subject: RE: Tour de France rider suffers blood clot, be aware
ChrisM - 2011-08-02 1:28 PM

In fact one study concluded that the majority of people getting blood clots were marathoners.

This would be astounding if true. The majority of all patients with blood clots are marathon runners? Or just the majority of athletes with DVTs?

2011-08-02 10:05 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware
alath - 2011-08-02 10:21 PM
ChrisM - 2011-08-02 1:28 PM

In fact one study concluded that the majority of people getting blood clots were marathoners.

This would be astounding if true. The majority of all patients with blood clots are marathon runners? Or just the majority of athletes with DVTs?

Different kind of marathon for this guy: http://www.foxnews.com/health/2011/08/01/xbox-gamer-dies-blood-clot-after-marathon-session/

Aside from a lot of anecdotal evidence, I can't find anything to suggest a link between endurance athletes and increased rates of blood clots.  Perhaps it's just because we seem to pay more attention when people perceived as otherwise healthy suffer from illnesses more associated with unhealthy people?

2011-08-02 10:07 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware

I don't want to address the doping issue simply out of respect to the rider and the reality it probably had nothing to do with his blood clot.

http://en.wikipedia.org/wiki/Virchow's_triad

Venous disease is a special interest of mine. Compression hose have been shown to be effective in non-ambulatory, bed ridden people but are probably less effective in people who walk. To decrease the risk of blood clots you should stay well hydrated, walk or activate the calf pumping mechanism at least every 2 hours and take an aspirin a day starting at the age of 40.



2011-08-02 11:53 PM
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Subject: RE: Tour de France rider suffers blood clot, be aware
apicek - 2011-08-02 10:05 PM

Different kind of marathon for this guy: http://www.foxnews.com/health/2011/08/01/xbox-gamer-dies-blood-clot-after-marathon-session/

Aside from a lot of anecdotal evidence, I can't find anything to suggest a link between endurance athletes and increased rates of blood clots.  Perhaps it's just because we seem to pay more attention when people perceived as otherwise healthy suffer from illnesses more associated with unhealthy people?

 

I think this is a huge reason. I have no idea what the actual statistics are, but I would hazard a guess that the majority of people that suffer from blood clots/heart problems/etc. are usually not considered to be very healthy. It's a bit of a surprise when prominent people in the active community come down with these types of illnesses, but it's probably at a much smaller rate than the general population. That's my wild guess at least.

2011-08-03 12:31 AM
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Subject: RE: Tour de France rider suffers blood clot, be aware

Geez....Chris is trying to keep the concept that longer endurance races can cause blood clots. By being aware it can happen, can help triathletes perhaps get diagnosed and treated sooner. Also knowing the possible ways to avoid them is helpful information for all of us.

Why bring up all these other points and arguments and dilute the message?

 

2011-08-03 6:58 AM
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Subject: RE: Tour de France rider suffers blood clot, be aware
KathyG - 2011-08-02 11:31 PM

Geez....Chris is trying to keep the concept that longer endurance races can cause blood clots. By being aware it can happen, can help triathletes perhaps get diagnosed and treated sooner. Also knowing the possible ways to avoid them is helpful information for all of us.

Why bring up all these other points and arguments and dilute the message?

 

x2

As the OP stated, DVT/PE is a problem that is typically thought to occur in people with hypercoaguability disorders, risk factors (birth control, etc), pregnant women, post op patients and older people who fly...but DVT (and resulting PE) are relatively common in athletes. It is true that doping can result in DVT/PE due to the "sludging" if you will of blood cells, but more common to result in DVT/PE: hemoconcentration due to dehydration, trauma (crashes, collisions, etc), inflammatory injury to blood vessels, etc.

Just a single case study attached if you are interested. Points out reasons why DVT/PE might be missed (mainly due to patients being outside of the general PE/DVT demographic, musculoskeletal pain due to the event itself, etc).

ETA: article too big. Brief abstract. From Journal of Emergency Medicine, April 2010.

"Abstract

Background: Demanding athletic events can contribute multiple risk factors to the development of deep venous thrombosis (DVT) in athletes. Objectives: To discuss risk factors for the development of DVT in athletes participating in athletic events. Case Report: We present the case of a young female athlete who had a DVT, complicated by pulmonary embolism, after participating in a half-Ironman triathlon. Conclusion: Our patient developed a DVT complicated by pulmonary embolism as a result of many factors relating to participation in a triathlon. Demanding athletic events can contribute different risk factors to the development of DVT in athletes. The diagnosis of DVT should be considered in any athlete presenting with leg pain, especially after a strenuous athletic event.

Keywords: triathlon; marathon; deep venous thrombosis; pulmonary embolism; athlete

Deep venous thrombosis (DVT) is a common diagnosis made in the emergency department (ED). The incidence has been estimated to range anywhere from 40 to 80 cases per 100,000 people annually, and all cases of venous thromboembolism, including pulmonary embolism, affect 1 in 1000 people per year (1). The true incidence of DVT is unknown secondary to inaccuracies of clinical diagnoses as well as the occurrence of many occult thromboses that resolve spontaneously. DVT is a diagnosis that should be considered in young, healthy athletes with symptoms, especially after demanding athletic events, despite the fact that it has rarely been reported ([2], [3] and [4]).

Case Report

 

A 33-year-old female triathlete with no past medical history presented to the ED complaining of 3 weeks of progressively worsening left lower extremity swelling and pain. She finished a half-Ironman triathlon 3 weeks prior. The morning after the race she drove a car about 5 h, stopping twice to walk. Her symptoms began shortly after the car ride. She also noted progressively worsening dyspnea on exertion and lightheadedness, all of which started after the leg symptoms. She was seen by a general practitioner 1 week after her symptoms began and was given a short course of corticosteroids for presumed lung inflammation. She did note mild improvement but, due to concerns regarding persistent leg pain, she obtained a referral to an orthopedist. On follow-up with the orthopedist 1 week later (after 2 weeks of symptoms), she was given a course of celecoxib (Celebrex; Pfizer Inc., New York, NY) and physical therapy. Her symptoms continued to worsen and prompted her to come to the ED. The patient had no significant medical history, including no prior DVT or malignancy. Her current medications included celecoxib and oral contraceptives. She denied smoking and illicit drug use. There was no family history of hypercoagulopathies.

On physical examination, her vitals signs were stable and she had an oxygen saturation of 100% on room air. She had a regular heart rate and rhythm and no murmurs, rubs, or gallops were appreciated. The lungs were clear to auscultation bilaterally. The left lower extremity was noted to be diffusely erythematous, warm, swollen, and tender to palpation to just above the knee. Pulses were equal in bilateral lower extremities. The rest of the physical examination was unremarkable.

An evaluation for suspected DVT with possible pulmonary embolism was initiated. An electrocardiogram was normal, with a sinus rhythm of 62 beats/min with no signs of right heart strain. Complete blood count, electrolytes, and coagulation studies were unremarkable. A bedside venous duplex ultrasound was done by the vascular surgery technician and was significant for an occlusive DVT in the superficial femoral vein through the popliteal vein, with a non-occlusive DVT in the common femoral vein of the left lower extremity. A computed tomography scan of the chest with contrast was significant for extensive bilateral central pulmonary emboli. She was admitted to the medical service and started on low-molecular-weight heparin and warfarin. She remained in stable condition throughout her hospital stay and the lower extremity swelling improved. She was later discharged on warfarin, and an outpatient hypercoagulability workup was negative.

Discussion

 Diagnosing deep venous thromboses and their sequelae are an integral part of emergency medicine. Venous thromboembolism occurs in about 1 in 1000 people per year, and 1–5% of those afflicted will die from complications, mainly pulmonary embolism (5). The diagnosis might have eluded the two physicians the patient visited previously because she was a young, healthy patient with few apparent risk factors. Her pain easily could have been attributed to musculoskeletal pain in light of the recently completed vigorous competition. The significance of her lower extremity swelling may not have been appreciated initially. In addition, elite athletes may not exhibit tachycardia from a pulmonary embolism secondary to their propensity to be bradycardic at baseline.

Virchow's triad of venous stasis, endothelial injury, and hypercoagulability can help to identify general risk factors for venous thrombosis. Endurance athletes are exposed to many of these factors during prolonged strenuous exercise, particularly a triathlon. Endurance competitions such as triathlons and marathons often expose patients to the risk factors of trauma, including repetitive microtrauma and increased endothelial injury, increasing the risk of thrombosis (6). Dehydration during these events can also lead to hemoconcentration. The relationship of hemoconcentration to thrombotic events is undetermined, but in combination with other factors, it may contribute to an increased risk of DVT in athletes. In many cases, including our patient, these effects are compounded by immobilization after exertion and frequent long distance travel to and from the actual competition (7).

Violent effort or prolonged, strenuous exercise causing a DVT is rare but well described in the literature, particularly for the upper extremity. Effort thrombosis of upper extremity vasculature results from microtrauma to the axillo-subclavian vein leading to activation of the coagulation cascade and subsequent DVT formation. This condition is also known as Paget-Schroetter syndrome (6). Similar mechanisms have been reported in case reports concerning the lower extremity ([2], [3] and [4]). An additional factor that may contribute to DVT formation is muscle hypertrophy, leading to compression of venous structures, leading to stasis. Use of hormonal therapy, as in our patient, adds a fourfold increase in risk (6). The role of corticosteroids in the development of DVTs is still somewhat controversial ([8], [9] and [10]).

Elite athletes often rest after an event and can be relatively immobilized. The effect of this relative immobilization after competition is compounded by having to travel long distances to competitions, as our patient did. Some studies have shown that the risk of DVT is the same for any prolonged length of travel > 4 h, whether by air, car, bus, or train (7). However, our patient did stop multiple times to walk and stretch, which should have been protective given the relatively short length of time of each driving segment ([11] and [12]).

Conclusion

Deep venous thrombosis can occur in young, healthy athletes presenting with lower extremity pain or swelling after strenuous exertion. This population, especially endurance athletes, is often exposed to multiple different factors leading to venous stasis and endothelial injury, thus increasing their risk for thrombosis. Many may go undiagnosed secondary to expectations of pain and swelling after endurance events. More research needs to be done to determine the incidence of deep venous thrombosis in athletes after demanding events like triathlons."

 



Edited by mndymond 2011-08-03 7:02 AM
2011-08-03 7:42 AM
in reply to: #3626602

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